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diagnosis rheumatology ana antibody management systemic differential patterns anca antibodies antineutrophil arthritis autoantibodies classification cryoglobulinemia cryoglobulins disease diseases laboratory muscle
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #SLE #Summary #diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... SSc, PM/SSc OS, Raynaud ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear ... #erythematosus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management Summary ... life-threatening • Treatment ... #Erythematosus ... Diagnosis #Management #Summary
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... CTD-ILD, IIM, Raynaud ... #Antibody #Testing ... #Cytoplasmic #Patterns
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... Antineutrophil cytoplasmic ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... SLE) - Antinuclear ... - CCP antibody testing ... and C serology testing
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... any time during treatment ... GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis
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