126 results
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
Tract: ↑ Ca2+ absorption ... , ↑ PO4- absorption ... , ↑ PO4- reabsorption ... , ↓ PO4- reabsorption ... , PO4- reabsorption
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
↑ intestinal absorption ... ↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption
Fluid and Water Secretion and Absorption in the GI Tract

#Fluid #water #Secretion #Absorption #reabsorption #GITract #diagnosis
Secretion and Absorption ... water #Secretion #Absorption ... #reabsorption #
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
intestinal calcium absorption ... and stimulates resorption ... Stimulate calcium reabsorption ... kidney, Stimulates resorption
GI Tract Secretions and Fluid Absorption
Dietary Input and Digestive Secretions:
 • Food and drink: 2000 mL
Secretions and Fluid Absorption ... 200 mL Water Reabsorption ... Secretions #Fluid #Absorption ... #Reabsorption #
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview

HCO3 reabsorptive failure
Lowering of threshold for HCO3 absorption in
Overview HCO3 reabsorptive ... threshold for HCO3 absorption
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Diabeta) 3 CARB ABSORPTION ... slows gut starch absorption ... tubule glucose reabsorption
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
• Increase Na reabsorption ... • Increase H2O absorption
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Miscellaneous - Bone Resorption ... - Calcium Reabsorption
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
increased bone Ca2+ resorption ... increased GI Ca2+ absorption