739 results
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... and stimulates resorption ... Stimulate calcium reabsorption ... Hypercalcemia #Malignancy #Pathophysiology ... Differential #Diagnosis #algorithm
Hypercalcemia - Hormones and Pathophysiology  
Calcitriol:
 • Bones: Enhances mineralization
 • GI Tract: ↑ Ca2+
- Hormones and Pathophysiology ... , ↑ PO4- reabsorption ... Kidneys: ↑ Ca2+ reabsorption ... , ↓ PO4- reabsorption ... Hypercalcemia #Hormones #Pathophysiology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
↑ bone reabsorption ... ↑ tubular reabsorption ... Hypophosphatemia: ↑ bone reabsorption ... ↓↓ tubular reabsorption ... Calcium #Phosphorus #pathophysiology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Miscellaneous - Bone Resorption ... - Calcium Reabsorption ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
The Pathophysiology of Fat Absorption and Causes of Malabsorption (steatorrhoea)

#Fat #Malabsorption #Pathophysiology #Differential #Steatorrhea #Diarrhea #Diagnosis
The Pathophysiology ... of Fat Absorption ... and Causes of Malabsorption ... Malabsorption #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
tubule (PCT) - Reabsorption ... Isosmotic reabsorption ... Secretion and reabsorption ... organic acids and bases ... Segments #Function #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... • Increase Na reabsorption ... • Increase H2O absorption ... nephrology #Effects #pathophysiology
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
block glucose reabsorption ... -4/fulltext #Pathophysiology ... SLGT2 #Inhibitors #Reabsorption
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... MGUS - Poor reabsorption ... Differential #Diagnosis #Algorithm ... #Causes
Nephron Reabsorption Sites
 • Proximal Convoluted Tubule
 • Proximal Straight Tubule
 • Thick Ascending Limb
 •
Nephron Reabsorption ... Bladder #Nephron #Reabsorption ... #pathophysiology