27 results
Hypereosinophilia (HE) Summary

 • Definition
 • When to Suspect?
 • A Partial Classification of Hypereosinophilia
 •
• A Partial Classification ... Hypereosinophilia • Diagnostic ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Responsive to Treatment ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders #Classification ... #differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Glucocorticoids, IL-1B, ATRA ... #Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... • Artifact (redo ... effect following treatment ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Sudan Black, Auer rod ... Amy Chung, MD, MSc ... #Diagnosis #Algorithm
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Disease Clinical triad ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment ... #rheumatology
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
with respect to arterial ... #Diagnosis #Rheumatology ... #Differential # ... Medium #Large #Classification
Medial Meniscus Bucket Handle Tear - MSK Radiology
Imaging Findings:
 • Truncation of the medial meniscus on
Handle Tear - MSK ... also seen on the axial ... in peripheral red ... Differential diagnosis ... #msk
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... syndrome Leg Pain Red ... #diagnosis #lower ... #extremity #msk
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Triggers: ATRA ... treatment Pathophysiology ... initiation • Differential ... Renal Failure Treatment ... #management #hematology