29 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... - inadequate production ... #dka #hhs #pathophysiology ... #comparison #endocrinology
Causes of hypophosphatemia - Differential Diagnosis
 • Increased losses: enhanced urinary phosphate excretion
 • Decreased input:
hypophosphatemia - Differential ... Enhanced endogenous production ... hypophosphatemia #Causes #Differential ... #Diagnosis #endocrinology
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Breast Discharge - Differential ... Lesion Autonomous Production ... Breast #Discharge #Differential ... Diagnosis #Algorithm #Endocrinology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... Increased Cell Production ... #Hypokalemia #Differential ... potassium #low #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
to excess TSH production ... Hyperthyroidism #endocrinology ... #pathophysiology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Primary - Over-production ... Secondary - Over-production ... Hyperuricemia #Differential ... Diagnosis #Algorithm #endocrinology
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
Ducts -> Milk production ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
-> surge in LH production ... Increased fluid production ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
Decreased FSH production ... to Increased LH production ... MenstrualCycle #pathophysiology ... HypothalamicPituitary #endocrinology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... cancer • Ectopic production ... Hypercalcemia #Malignancy #Pathophysiology ... #Differential #