10 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
partial mu-opioid receptor ... a kappa-opioid receptor ... the kappa-opioid receptor ... full mu-opioid receptor ... due to mu-opioid-receptor
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
specific GABAA receptor ... , acting like benzodiazepines ... at 5-HT receptors ... #medications #pharmacology ... #comparison #table
Muscarinic Receptor Agonists and Antagonists 
Muscarinic Receptor Agonists
Methacholine
 • Diagnosis of bronchial airway
Carbachol
 • Glaucorna (topical
Muscarinic Receptor ... Muscarinic Receptor ... syndrome Muscarinic Receptor ... ., AV block) • ... #Table
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... cytokine synthesis, e.g ... Basiliximab - IL-2 receptor ... Immunosuppressant #Drugs #Pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... Mechanisms of Action ... Ozempic), or daily tablet ... featured #GLP1 #Receptor ... #Agonists #Pharmacology
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Summary of actions ... at muscarinic receptors ... at muscarinic receptors ... #Pharmacology # ... Table #Summary
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Mechanisms of Action ... therapy with GLP-I receptor ... agonist • Personal ... DPP4 #Inhibitors #Pharmacology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... • Heart - ↑ AV ... Adrenoceptor #adrenergic #receptors ... #actions #pharmacology ... pathophysiology #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Mineralocorticoid Receptor ... ) Vasopressin Receptor ... Agonist V1 receptor-agonist ... Hypovolemic shock V2 receptor-agonist ... disorders Vasopressin Receptor
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
of adrenergic receptors ... muscarinic Ach receptors ... Ideosyncratic reaction ... cessation of dopamine agonists ... mutations in ryanodine receptor