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diagnosis algorithm management treatment hypocalcemia nephrology cardiology gout hyperuricemia low malignancy rhabdomyolysis 21hydroxylasedeficiency 21ohd acidosis acromegaly acute aki alkaline alp
Hypocalcemia - Workup Algorithm Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1 #Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... #Workup #Algorithm ... #differential # ... diagnosis #endocrinology ... #causes #calcium
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
Hypercalcemia Workup ... and Differential ... #Workup #Differential ... Diagnosis #algorithm #endocrinology ... #calcium
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Pseudohyperparathyroidism, Renal ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Differential Diagnosis ... Autosomal Dominant Calcium ... Other • Excess Calcium ... #Differential # ... Diagnosis #Algorithm #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Differential Diagnosis ... Tumors: Lung, SCC, renal ... Bony Mets - Calcium ... Diagnosis #Algorithm #causes ... #endocrinology
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... , adrenal, prostate ... #Causes #endocrinology ... #diagnosis #differential
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... #workup #differential ... #diagnosis #endocrinology ... #calcium #elevated
Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of ... Malignancy - Pathophysiology ... and intestinal calcium ... Mediated - Stimulate calcium ... #Differential #
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... thyrotoxicosis, adrenal ... #Causes #Differential ... #Diagnosis #Endocrinology
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 Causes of Hypocalcemia - Differential Diagnosis Algorithm • Extravascular: Pancreatitis, surgery, acute phosphate intake and renal
Causes of Hypocalcemia ... - Differential ... phosphate intake and renal ... Drug induced: Calcium ... #Differential #
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