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diagnosis differential cardiology deficiency antiarrhythmics hematology management pharmacology anemia chf gastroenterology heartfailure hfref pathophysiology approach celiac disease endocrinology fe gastronintestinal
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... reduce speed of ion ... prolong AV node repolarization ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... reduce speed of ion ... interval (delays time repolarization ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization
Vaughan Williams Classification ... Class I (Ia, Ib ... Blockade • Slows depolarization ... VaughanWilliams #Classification ... #Classes #cardiology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... effect following treatment ... malignancy • Iron ... #Causes #Hematology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Inflammatory Disease (IBD ... , cancer) #Iron ... differential #diagnosis #causes
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Differential Diagnosis Algorithm ... cancer, ulcer, IBD ... Differential #Diagnosis #Causes ... #Fe #algorithm
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Diagnosis and Treatment ... Algorithm Diagnosis ... ng/mL (absolute ID ... diagnosis #management #algorithm ... #cardiology #treatment
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
→ Inflammation causes ... ng/mL (absolute ID ... 20% (functional ID ... ) Treatment - IV ... endpoint of all-cause
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Volume (<80 fL) • Iron ... #Anemia #MCV #Classification ... #Causes #Hematology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Disease - Diagnosis Algorithm ... celiac disease • Iron-deficiency ... unresponsive to treatment ... without discernable cause ... Inflammatory (IBD
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