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diagnosis differential systemic sle erythematosus symptoms management antibodies antinuclear classification comparison dermatology hematology mnemonic myositis vasculitis autoimmune criteria hcq hydroxychloroquine
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... , Drug-induced Lupus ... , Polymyositis/Dermatomyositis ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
Findings in Dermatomyositis ... - Heliotrope sign ... V-neck sign or ... #Dermatomyositis ... #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... dermatomyositis ... polyangiitis without renal ... antibodies #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Antinuclear Antibody (ANA ... Arthritis R Renal ... sle #systemic #lupus ... erythematosus #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Diseases: • Systemic lupus ... Cytomegalovirus • Epstein-Barr ... Differential #Diagnosis #Hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... Erythematosus Clinical and ... - SEROSITIS - RENAL ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
, Drug-induced Lupus ... Speckled: Systemic lupus ... , Polymyositis/Dermatomyositis ... , Drug-Induced Lupus ... #patterns #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... Anti-retrovirals, Gemcitabine Lupus ... joint aches • +ANA ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus ... erythematosus #signs ... symptoms #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... hemolysis • Renal ... low C4, Low C3 and ... Erythematosus #diagnosis #rheumatology
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