16 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... activity Anti-Ro ... Hydroxychloroquine *Short ... #Lupus #Erythematosus ... #SLE #Summary #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology ... signs #symptoms #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Disease, PRES Pathophysiology ... permeability Diagnosis ... RheumOnePagers) #Systemic
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... 40% Target: SS-A/Ro ... -15% If SLE is clinically ... autoantibodies #Systemic ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... • Malar rash - spares ... #Diagnosis #Rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... (PBC), or with systemic ... lupus erythematosus ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Pathomechanics and Clinical ... LowAnkleSprain #Sports ... #MSK #orthopedics ... Grading #Grades #Diagnosis ... #pathophysiology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
is oftentimes systemic ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Overuse Tendinopathy: Pathogenesis and clinical findings
 • Intrinsic factors: Age, Body weight, Nutrition, Gender, Anatomical variations,
Pathogenesis and clinical ... Joint laxity, Systemic ... factors: Occupation, Sport ... #Tendinopathy #pathophysiology ... #msk
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Antibodies: Anti-Ro ... Antibodies: • Anti-Ro ... salivary ducts Clinical ... Central nervous system ... phenomenon (16%) MSK