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management differential rheumatology clinical nephrology algorithm msk erythematosus radiology systemic mri sle acute aki ana antinuclear antiphospholipid barre bee guillain
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... and treatment can ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
activity Anti-Ro ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... #SLE #Summary #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... 40% Target: SS-A/Ro ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... • Hepatorenal syndromes ... IgA, post-strep, lupus ... legionella) • Immune (lupus
Causes of Myocarditis Infectious Etiologies: • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Immunological Syndromes ... Churg-Strauss syndrome ... Sarcoidosis, Systemic lupus ... #differential #diagnosis ... #cardiology #causes
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... Hypothalamic or thalamic syndromes ... disorders (Systemic lupus ... erythematosus, Sjögren syndrome
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Vasculitis, Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... - Differential Diagnosis ... arthritis • Systemic lupus ... Post-cardiac injury syndrome ... #Cardiology
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