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287
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Antibody) and
ANCA
... Anti-dsDNA (in 70% of
cases
... seen in 30—70% of
cases
... Anti-
Ro
/SSA ... Antinuclear #Antibody #
ANCA
Anti-Smith, Anti-
Ro
... Syndrome: Anti-
Ro
... Polymerase Ill •
ANCA
... Vasculitis: P-
ANCA
... perinuclear), C-
ANCA
Disease Associations
ANA
... SLE Anti-SSA (
Ro
... Graves' disease c-
ANCA
... granulomatosis p-
ANCA
Diagnosis Framework
ANCA
... : • C-
ANCA
: GPA ... Wegener's) • P-
ANCA
... diagnosis #nephrology #
causes
pathophysiologic
causes
... Negative IF): • PR3-
ANCA
... (C-
ANCA
): GPA > ... > eGPA • MPO-
ANCA
... (P-
ANCA
): eGPA,
Associated -
ANCA
... Granulomas -
ANCA
... Granulomas -
ANCA
... tract, and often
causes
... (MPO) - (C-
ANCA
osmolarity If
cause
... Glomerulonephritis / Vasculits:
ANCA
... ,
ANA
, Anti-GBM, ... Diagnosis #nephrology #
causes
Antinuclear (
ANA
... activity Anti-
Ro
Causes
of Purpura ... cryoglobulins, IgA),
ANCA
... nonpalpable #palpable #
Causes
10% of all lupus
cases
... Workup: -
ANA
... - Rare -
pANCA
... Discontinuation of
causal
... Positive in 60-80% of
cases
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