54 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... body-like: - Neurologic ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... body-like: • Neurologic ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... first-line treatment ... awaiting confirmatory testing ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
- Fever >= 39C lasting ... - Typical skin rash ... non-pruritic, salmon-pink rash ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... ANA Labs: • ↑ESR ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Conjunctivitis, Mucositis, Rash ... Criteria - Fever lasting ... Polymorphous rash ... KD #vasculitis #rheumatology ... #management #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
) - Diagnosis and ... disorders • Testing ... diazepam • EMG testing ... Person Syndrome Treatment ... #treatment #neurology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... Manifestations: Malar rash ... Workup: - ANA ... life-threatening • Treatment ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
testing for HLH-associated ... • Bicytopenia Treatment ... treating the insulting ... #management #treatment ... #hematology