612 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... (Diffuse) Anti-Sm ... - SLE Anti-SSA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 10% of all lupus cases ... Workup: - ANA ... cutaneous DIL), anti-Sm ... Discontinuation of causal
Causes of Nausea and Vomiting - Differential Algorithm #Diagnosis #EM #IM #Causes #Nausea #Vomiting #Differential #NonGI
Causes of Nausea ... and Vomiting - ... Differential Algorithm ... Diagnosis #EM #IM #Causes ... Differential #NonGI #Algorithm
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... phenomenon Anti-Sm ... higly specific for SLE ... rheumatology #table #ANA
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... Scl70 (in some cases ... pattern: - SjS, SLE ... UCTD - Smith, Sm ... Scl-70 (in some cases
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... IMMUNOLOGIC CRITERIA - ANA ... ELISA) - Anti-Sm ... of antibody to Sm ... #Rheumatology #SLE
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Anti-dsDNA (in 70% of cases ... Anti-Sm (Smith) ... in drug-induced SLE ... seen in 30—70% of cases
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-dsDNA, Anti-Sm ... Antinuclear Antibody (ANA ... #IMDAMNSHARP #sle
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm
 • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... Differential Diagnosis Algorithm ... HIV, CMV, Hep B and ... spondylitis, RA, SLE ... #Nephropathy #Causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Differential #Diagnosis #Algorithm ... #Causes #Hematology