24 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication ... medications and ... #Pathophysiology ... #Drug #Endocrinology
Secondary causes of Hypertension
 • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Hypertension • Medications ... , Drugs, Chemo: ... Pseudopheochromocytoma - respond to SSRIs ... , Geller syndrome ... , Gordon syndrome
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... renal Fanconi syndrome ... panitumumab) #Drugs ... hypomagnesemia #Medications ... differential #diagnosis #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... activities • Diuretic ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Familial: Bartter syndrome ... and Gitelman syndrome ... Hypomagnesemia - Acquired: Medications ... renal transplant, Diuretic ... diagnosis #causes #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... #Diuretics #Medications ... summary #table #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Correction of diabetic ... renal disease Drugs ... disorders: - Syndrome ... #differential #medications ... #drugs #pharmacology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
• Refeeding syndrome ... Thyrotoxicosis Medications ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Renal losses, Diuretic ... Hypothyroidism, Stress, Drugs ... , Syndrome of inappropriate ... • Nephrotic syndrome ... Algorithm #Causes #nephrology
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
- Metabolic syndrome ... hyperkalemia (ACEI, ARB, diabetes ... failure - Co-medication ... - Metabolic syndrome ... antihypertensive #medications