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clinical pocus diagnosis echocardiogram s4c cardiology management differential ultrasound physicalexam video rheumatology pericardial algorithm causes effusion obgyn gastroenterology radiology table
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
of Scleroderma (SSc ... renal crisis (SRC ... #Scleroderma #SSc
Diagnostic Criteria for Scleroderma Renal Crisis 1. New onset blood pressure >150/85 mm Hg OR increase
typical features of SRC
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
catastrophic APS, SRC
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Renal Crisis (SRC ... MithuRheum #SRC
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
SjS, SLE, DM, SSc ... , PM/SSc OS, MCTD ... pattern: - SSc ... , PBC/SSc OS ... pattern: - SSc
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-JO-1, Others: SRP ... Systemic Sclerosis, SSc
Acute Kidney Injury - RIFLE and AKIN Criteria for Diagnosis and Classification of AKI • AKIN
- Increase in SCr ... or increase in SCr ... - Increase in SCr ... - Increase in SCr
Superior Vena Cava Syndrome on Physical Exam Prominent dilated collateral veins are seen bypassing the SVC obstruction #SVC
bypassing the SVC ... obstruction #SVC
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 Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
• Increase in SCr ... • Increase in SCr ... or increase in SCr ... m2 • Stable SCr
Chronic SVC Stenosis with Caudal Blood Flow of Dilated Abdominal Veins 60 y/o hx of seizures &
Chronic SVC Stenosis ... collaterals - SVC ... cephalad (towards SVC ... ) - SVC obstruction ... stenosis of his SVC
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