660 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
, SLE, DM, SSc, ... PM/SSc OS, MCTD, ... -52 (Ro52), SSA- ... 60 (Ro60), SSB ( ... differential #diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Anti-Smith, Anti-Ro (SSA ... ) and Anti-La (SSB ... ), Anti-La (SSB) ... Autoantibodies #Rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
, SLE, DM, SSc, ... PM/SSc OS, MCTD, ... -52 (Ro52), SSA- ... 60 (Ro60), SSB ( ... differential #diagnosis #rheumatology
Colonoscopy Followup Intervals 
10 years: Normal colonoscopy, ≥ 20 HP < 10mm
7-10 years: 1-2 adenomas <
-10 years: 1-2 SSPs ... adenomas, 5-10 SSPs ... , Adenoma or SSP ... grade dysplasia, SSP ... 10 adenomas SSPs
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... Table #Pulmonary #Rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
lupus (90%) Anti-SSA ... 30-40% Target: SS-A ... Sjogren Anti-SSB ... Associated with SLE-SSc-AlM ... erythematosus #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Sjogren's Syndrome (SS ... or scleroderma (SSc ... ANA #patterns #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Sm - SLE Anti-SSA ... (Ro), Anti-SSB ... diagnosis #table #rheumatology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome (ASS ... Managment #algorithm #Rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
/AMA: • PBC, SSc ... , PBC/SSc OS, PBC ... : • SLE, SjS, CTD-ILD ... polar: • SLE, SjS ... differential #diagnosis #rheumatology