17 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... rheumatoid arthritis (RA ... ) or systemic lupus ... Xeroderma (Dry skin ... #Diagnosis #Signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(15%) Skin (85% ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... lesions Abdominal pain ... erythematosus #signs
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
gangrenosum • IBD • RA ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #pain #skin #rashes ... differential #diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... Anticoagulant (LAC) • Sjogren ... ribonucleoprotein) • RA ... • Scleroderma (Systemic ... Polymerase Ill • ANCA Vasculitis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Lyme disease, Vasculitis ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... - 10% SLE or RA ... lupus erythematosus ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... vesicular eruption - Joints ... lupus erythematosus ... purpura: strong sign ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Polyarteritis Nodosa (PAN ... Rheumatoid Arthritis (RA ... ), Systemic lupus ... Differential #Diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... dermatomyositis, Sjogren ... Arthritis: • Joint ... pain • Swan neck
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Inflammation and pain ... of the joints ( ... Leukocytoclastic vasculitis ... - Lupus - Leukemia