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management differential erythematosus lupus monoclonal sle vasculitis mgus systemic classification criteria disease gammopathy nephrology signs symptoms cancer cryoglobulinemia cryoglobulinemic emergencies
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Sausage-like" hemorrhagic retinal ... Hyperuricemia • Acute renal ... #differential #diagnosis
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... capillary leak syndrome ... Cryoglobulinemia Renal-centered ... #hematology #oncology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... • Scleroderma renal ... #differential #diagnosis ... #hematology #hemolysis
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
gammopathy of renal ... change disease • Hematologic ... Capillary leak syndrome ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
antiphospholipid syndrome ... Erythematosus (total 50, renal ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... not related to clinical ... Hyperviscosity syndrome ... arthritis • Renal ... #Rheumatology #
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
dL the ULN R - Renal ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Burr cells - Renal ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
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