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management differential oncology signs systemic lupus monoclonal sle erythematosus mgus nephrology vasculitis causes comparison gammopathy summary workup cancer classification complications
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
• Scleroderma renal ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... • Scleroderma renal ... #differential #diagnosis ... #hematology #hemolysis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
severe disease & renal ... block • Sjogren syndrome ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
antiphospholipid syndrome ... Erythematosus (total 50, renal ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal
Approach to Gout Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals Treatment: • Weight loss, diet, d/c culprit
Approach to Gout Diagnosis ... Acute and chronic treatment ... Urate nephropathy, renal ... NUIM_Chiefs #gout #diagnosis ... #ULT #rheumatology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... HYPOTENSION -> renal ... vasocontriction-> decreased renal ... renal ischemia ... Cast formation: Renal
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Abdominal pain (20%) Renal ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... #management #hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology
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