12 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... Abnormal Coagulation Tests ... DrEricStrong #Algorithm ... #Laboratory #Hematology ... #Diagnosis #Workup
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... inhibitor • Liver ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... Alcoholic Hepatitis (AH ... Presence of atypical laboratory ... tests (e.g., AST ... #hepatology #criteria
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... → liver test abnormalities ... #Diagnosis #hepatology ... #algorithm #Transaminitis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value is low, tests ... performed PT, PTT ... leukocytosis with a left shift ... #Workup #Hematology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... hepatocellular injury ... #LFTs #Laboratory ... Interpretation #diagnosis ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT ... #Chemistry #Tests ... #Laboratory #Metabolism ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... cases: INR/PT, aPTT ... (liver disease, ... Refractory ITP, ... Causes #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
venipuncture sites Laboratory ... DIC • Severe Liver ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... treatment #management #hematology