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diagnosis differential hyperkalemia management hypokalemia table high algorithm hypomagnesemia hypomg rhabdomyolysis summary abortive agents anesthesia anesthesiology binder binders binding classes
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Thyrotoxicosis Medications ... vomiting) • Low K ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... sparing diuretics ... Intracellular Shift ... Medications 2. ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... sparing diuretics ... Intracellular Shift ... Medications 2. ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... of K (Succinylcholine ... pathophysiology #pharmacology ... #potassium #medications
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+K+ ... Piretanide Potassium ... #Pharmacology # ... nephrology #conversion
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... renal disease Drugs ... #differential #medications ... #drugs #pharmacology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... plasma insulin (treatment ... Conn's, Liddle's), Drugs ... differential #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , K-sparing diuretics ... only if no clear cause ... STOP offending medications ... #potassium #nephrology
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