21 results
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... Pediatrics Patient - Differential ... on texture of skin ... migrans: • Target sign ... #skin #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... Discoid skin ... #joint #pain #skin ... #rashes #differential
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... - with the skin ... with Systemic Lupus ... should have other symptoms ... like “butterfly rash
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
neuropathies • Skin ... Subcutaneous nodules, lupus ... dysrhythmias • Ophthalmologic ... Sarcoidosis #Diagnosis #Symptoms ... #Signs #Pulmonary
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Fever, malaise • Rash ... testing • No symptoms ... aortic aneurysm, arteritis ... lesions in bone, skin ... #signs #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Manifestations: - Arthritis ... 69% - Malar rash ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... RA) or systemic lupus ... / Symptoms: - ... Xeroderma (Dry skin ... #Symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
plugging -> Discoid Rash ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications