21 results
diagnosis pulmonary algorithm antibodies causes classification renal ana antinuclear dermatology nephrology syndromes systemic workup acute aki antibody antineutrophil aortitis arthritis
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
- C-ANCA pattern ... antibody) - P-ANCA ... PR3 Anti-GBM disease ... #CANCA #PANCA # ... PR3 #Diagnosis #Rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... Vasculitis: + MPO-ANCA ... Diagnosis: Systemic rheumatic ... purpura: strong sign ... #rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... polyangiitis, Microscopic ... polyangiitis) - ANCA-negative ... erythematosus, Rheumatoid ... testing: anti-ANCA
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Nodosa (PAN), ANCA ... associated vasculitis ... (rare) • Rheumatic ... #Diagnosis #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... inflammation: • Microscopic ... StanfordChiefs #ANCA ... #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... glomerulonephritis 90%: - ANCA ... Double Positive (ANCA ... Antiphospholipid Syndrome, Rheumatoid ... Syndromes #Mimics #Differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... #differential #
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of Vasculitis ... Vasculitis of ... small vessels - ANCA-associated ... granulomatosis - microscopic ... Vessels #Diagnosis #Rheumatology
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