16 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA), microscopic ... polyangiitis without renal ... involvement - PR3>MPO Microscopic ... PR3 Anti-GBM disease ... PR3 #Diagnosis #Rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... polyangiitis, Microscopic ... vasculitis, Behcet ... erythematosus, Rheumatoid ... #Syndrome #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Vasculitis: • ... Microscopic polyangiitis ... polyangiitis without renal ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... ): • Microscopic ... Diagnosis: Systemic rheumatic ... purpura: strong sign ... #rheumatology #
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Nodosa (PAN), ANCA ... associated vasculitis ... (rare) • Rheumatic ... #Diagnosis #rheumatology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Syndromes and Mimics - Differential ... glomerulonephritis 90%: - ANCA ... Double Positive (ANCA ... Antiphospholipid Syndrome, Rheumatoid ... Syndromes #Mimics #Differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... with different rheumatic ... • Rheumatic Diseases ... #patterns #rheumatology ... #diagnosis #differential
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... • ANCA Associated ... : - Microscopic ... : • Behcet Disease ... #dermatology #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Algorithm and Differential ... dipstick, urine microscopy ... clinical context and signs ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM