12 results
Crystal cast in patient with AKI and TLS on Urine Microscopy

Randy Luciano MD, PhD @RandyLucianoMD

#TLS #Crystal
Crystal cast in ... patient with AKI ... and TLS on Urine ... #casts #crystalluria ... #Urine #Microscopy
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... acute and chronic kidney ... compounds (e.g. heme, bilirubin ... #Urine #Microscopy
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Kidney Injury (AKI ... Epithelial cell casts ... myeloma) • Urate crystals ... polyangiitis /microscopic
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Approach to Acute Kidney ... cases are caused ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... , crystals, protein
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... , urine microscopy ... osmolarity If cause ... , haptoglobin, bilirubin ... imaging #Acute #Kidney
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Bilirubin. ... Microscopic exam ... • Urinary casts ... (AKI) FE Na < ... #UNa #casts #glucosuria
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
white blood cell casts ... renal tubular cell casts ... or pigmented casts ... Intrarenal: stones, crystals ... #Injury #AKI #Differential
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... - Urinalysis/microscopy ... UOP/weights - Urine ... rhabdo/TLS) Causes ... #Differential
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... + myoglobin AKI ... Cast formation: ... nephrotoxicity to kidney