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diagnosis nephrology algorithm kidney hematuria kidneyinjury renal workup acutekidneyinjury atlas blood checklist drugs examination glucosuria instructions key leucocyteesterase management medications
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... , urine dipstick ... , urine microscopy ... / urinary sediment ... osmolarity If cause
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Kidney Injury ( ... circulating volume, Urinary ... cases are caused ... for WBCs, RBCs, casts ... , crystals, protein
Urinalysis & Urine Sodium Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Microscopic exam ... • Urinary casts ... Acute Kidney Injury ... (AKI) FE Na < ... #UNa #casts #glucosuria
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Kidney Injury (AKI ... AKI) - Acute increase ... Epithelial cell casts ... myeloma) • Urate crystals
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... #AKI #Differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria - Differential ... clots ➔ Lower Urinary ... (Urinalysis or dipstick ... Immune mediated injury ... hematuria: - RBC casts
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... UOP/weights - Urine ... pre-renal) - Urinary ... #Differential
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Kidney Injury ( ... Bactrim), NSAIDs • Crystal ... contraction, and/or ↑ urinary ... sphincter tone: • Opiates ... #pharmacology #differential
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... #Casts #Differential
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