14 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... AcuteKidneyInjury #AKI ... Pathophysiology #Pharmacology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Kidney Injury ( ... sphincter tone: • Opiates ... decongestants) • Any drug ... #Acute #Kidney ... #Drugs #pharmacology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... Diagnosis Framework ... Infection-mediated, Drug-induced ... #Acute #Kidney ... #Injury #Differential
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury ... • Drug induced ... acute kidney injury ... 24-72 hours of drug ... kidney injury is
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Kidney Injury ( ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential Diagnosis ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Kidney Injury ( ... AKI ) - Prerenal ... tubular necrosis • Drugs ... nephritis • Drugs ... #Acute #Kidney
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... hepatorenal, sepsis • Drugs ... #Kidney #Injury
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Skin involvement, Kidney ... exposure to HDS, drugs ... non-essential drug ... dechallenge • Acute
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... Avoiding nephrotoxic drugs ... appropriate) #Acute ... #Kidney #Injury ... #AKI #Differential