11 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI ... #Pharmacology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... PRE-Renal AKI ... Infection-mediated, Drug-induced ... POST-Renal AKI ... #nephrology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Injury ( AKI ) ... tubular necrosis • Drugs ... • Prolonged hypotension ... nephritis • Drugs ... /phimosis #Diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute Kidney ... Differential Diagnosis ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
systemic disease or drugs ... • Prolonged hypotension ... • Drugs • Toxins ... Nephritis (AIN) • Drugs ... #nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Injury • Drug ... 24-72 hours of drug ... #Vancomycin #AKI ... #pharmacology # ... toxicology #diagnosis
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... artery stenosis • Drugs ... • Diabetes • Hypertension ... eosinophiluria) • Drugs ... KidneyDisease #Nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
- Differential Diagnosis ... (multi-drug resistance ... ) Renal Parenchymal ... Nephritic syndrome • AKI ... HTN #Secondary #Nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Glomerular Disease: Drug ... @kdjhaveri #DrugInduced ... #differential #diagnosis