40 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... Pathophysiology #Pharmacology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... Antimicrobials Drug-induced ... panitumumab) #Drugs ... #differential #diagnosis ... #nephrology #Causes
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... #nephrology #potassium
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Drugs II. ... Drug-induced hyperkalemia ... anti-inflammatory drugs ... #differential #diagnosis ... #causes #nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Glomerular Disease: Drug ... #differential #diagnosis ... #algorithm #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
- Differential Diagnosis ... AKI: • Hypovolemia ... Infection-mediated, Drug-induced ... #Differential #Diagnosis ... #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... #differential #diagnosis ... pathophysiology #pharmacology ... #medications #druginduced
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... trauma • Drugs ... Malignancy True hypovolemia ... GI losses • Renal ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... trauma • Drugs ... Malignancy True hypovolemia ... GI losses • Renal ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
- Differential Diagnosis ... Algorithm Hypovolemia ... Hypothyroidism, Stress, Drugs ... #Differential #Diagnosis ... Algorithm #Causes #nephrology