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differential causes algorithm aki acute management kidney medications kidneyinjury hyperkalemia hyponatremia potassium acidosis chronic high hypokalemia hypomagnesemia secondary syndrome treatment
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron #DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... Pathophysiology #Pharmacology
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Glomerular Disease: Drug ... #differential #diagnosis ... #algorithm #nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
of Acute Kidney Injury ... tubular necrosis • Drugs ... nephritis • Drugs ... /phimosis #Diagnosis ... #Differential #Nephrology
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... - Differential Diagnosis ... Infection-mediated, Drug-induced ... Acute #Kidney #Injury ... #nephrology
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
• Drug induced ... 24-72 hours of drug ... particularly underlying renal ... #toxicology #diagnosis ... #management #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
of Acute Kidney Injury ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... panitumumab) #Drugs ... #differential #diagnosis ... #nephrology #Causes
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... nephropathy • Drugs ... #algorithm #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
of Acute Kidney Injury ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs ... #KidneyInjury #Nephrology
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