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differential nephrology causes algorithm acute management injury kidney medications potassium acidosis hyponatremia kidneyinjury renal rhabdomyolysis treatment aniongap chronic druginduced high
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron #DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology ... #Pharmacology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... renal failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... nephropathy • Drugs
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... panitumumab) #Drugs ... #differential #diagnosis ... #nephrology #Causes
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Kidney Injury (AKI ... - Differential Diagnosis ... Infection-mediated, Drug-induced ... #Differential #Diagnosis ... #nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sensitive) • AKI ... , AKD, rapidly progressive ... sediment • Received drug ... AIN #Algorithm #nephrology ... #diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Drugs II. ... Drug-induced hyperkalemia ... anti-inflammatory drugs ... #differential #diagnosis ... #causes #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs ... #KidneyInjury #Nephrology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Liver Failure • Hypercalcemia ... Pulmonary Disease Neurologic ... Anti-Depressants • Drug ... Alcohol) • Drug ... Malnutrition / Drug
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #nephrology
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