14 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI ... #Pharmacology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... Diagnosis Framework ... Infection-mediated, Drug-induced ... #Acute #Kidney ... #nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Injury • Drug ... 24-72 hours of drug ... #Vancomycin #AKI ... #pharmacology # ... toxicology #diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
causes of Acute Kidney ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute Kidney ... Differential Diagnosis ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Causes of Acute Kidney ... Injury ( AKI ) ... tubular necrosis • Drugs ... nephritis • Drugs ... /phimosis #Diagnosis
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Glomerular Disease: Drug ... @kdjhaveri #DrugInduced ... #differential #diagnosis ... #algorithm #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
(AKI) - Differential ... Diagnosis Framework ... hepatorenal, sepsis • Drugs ... #Injury #AKI #Differential ... #Diagnosis #nephrology