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Drug-induced renal disorders - The most commonly used nephrotoxic drugs

#Pharmacology #Nephrotoxicity #Drugs #Medications #Most #Common #DrugInduced
Drug-induced renal ... used nephrotoxic drugs ... #Pharmacology ... Nephrotoxicity #Drugs ... #Table #List
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology ... #Pharmacology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... Infection-mediated, Drug-induced ... #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
(AKI) - Acute increase ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs ... #Nephrology #Differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #Diagnosis #nephrology
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia • Hapten (Drug ... Omeprazole, Sulfa drugs ... #diagnosis #pharmacology ... #table
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... Understand vasoactive drug ... shock #Vasoactive #Drugs ... inopressors #diagnosis ... management #comparison #table
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach to Acute ... sensitive) • AKI ... sediment • Received drug ... AIN #Algorithm #nephrology ... #diagnosis
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Kidney Injury ( AKI ... tubular necrosis • Drugs ... nephritis • Drugs ... /phimosis #Diagnosis ... #Nephrology