22 results
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia • Hapten (Drug ... Omeprazole, Sulfa drugs ... #diagnosis #pharmacology ... #table
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... Understand vasoactive drug ... shock #Vasoactive #Drugs ... inopressors #diagnosis ... #table
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Transfusion reactions, Drug-associated ... Membrane Defects, Drugs ... Enzyme Defects: G6PD ... #Diagnosis #hematology
The RIGID patient: tetanus mimics
 - Serotonin Syndrome
 - Neuroleptic Malignant Sx
 - Malignant Hyperthermia
 -
Hyperthermia - Drug-induced ... tetanus #mimics #comparison ... #table #rigidity ... rigid #patient #differential ... #diagnosis
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... delayed HTR • Drug-induced ... Defects • G6PD ... • PNH • Drug-induced ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... Diagnosis Framework ... Spherocytosis, G6PD ... Orotic aciduria, Drugs ... #Diagnosis #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... Complement-mediated TMA - Drug-induced ... Microangiopathy #TMA #hematology ... #differential # ... diagnosis #HUS
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... G6PD, pyruvate kinase ... AIHA: warm, cold, drug ... #Diagnosis #causes ... classification #hematology
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Fever, wheezing • Drug ... antibiotics, illicit drugs ... Diseases #pulmonary #differential ... #diagnosis #comparison ... #table #eosinophilia