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diagnosis differential algorithm table management aflp anemia dermatology extravascular hellp intravascular obstetrics oncology pregnancy rheumatology thrombocytopenia ttphus acute anticholinergics antiphospholipid
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... uremic syndrome ... infection) - Drugs ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... delayed HTR • Drug-induced ... Sickle cell • Unstable ... Diagnosis #Algorithm #Causes ... #Hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Production • Hemolysis ... • Sepsis • Drugs ... • Gilbert's Syndrome ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , PCH, Evans Syndrome ... Membrane Defects, Drugs ... Thalassemias, Unstable ... Differential #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
defects. 1) HELLP (Hemolysis ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... defects. 1) HELLP (Hemolysis ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... evaluation or workup ... 1,500 cells/µL Workup ... asthma, allergy, drug ... Differential #diagnosis #hematology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... set of symptoms) caused ... by specific medications ... barbituates, “Z-drugs ... Toxicology #Toxidromes #Comparison
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Drug induced ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... spotted fever • Drug ... Differential #Diagnosis #hematology
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