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nephrology diagnosis differential akd aki algorithm causes chronic complications definitions framework hepatology hepatorenal hrs hrsaki hrsckd hrsnaki hyperkalemia hyperphosphatemia hyperuricemia
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
, AKD Acute Kidney ... • GFR < 60 ml/min ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
maintaining baseline GFR ... setting of modest GFR ... GFR > 30 and complete ... avoidance with GFR ... #Kidney #renal
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
e.g. diuretics, NSAIDs ... haematuria, Normal renal ... months - eGFR ... ascites • HRS-CKD ... - eGFR < 60ml
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic Kidney ... function (eGFR ... eosinophiluria) • Drugs (NSAlDs ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... acidosis, DKA Kidney ... Disease: • AKI, CKD ... Increased Renal ... Hypoparathyroidism, Acromegaly, FGFR
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... Complications #Gout
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... esp w oliguria / GFR ... Labs: BMP (Assess GFR ... status to improve GFR ... sufficient if intact GFR
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