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differential acute algorithm causes workup biomarkers calculation chronic clearance cockcroftgault creatinine definitions equations framework hepatology hepatorenal hrs hyperkalemia hyperphosphatemia injury
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
(AKD): • AKI, ... OR • GFR < 60 ... /AKD/CKD • No ... #CKD #AKD #Definitions ... #nephrology #acute
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR ... , CKD • Obesity ... #renal #diagnosis
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
as a marker of kidney ... accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... #Diagnosis #Nephrology
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 Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
is increased in CKD ... prolonged NSAID use in CKD ... with GFR > 30 and ... avoidance with GFR ... #renal #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
- Differential Diagnosis ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD ... KidneyDisease #Nephrology
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
acidosis, DKA Kidney ... Disease: • AKI ... , CKD Increased ... Renal Phosphate ... Workup #phosphate #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause of AKI ... #Injury #AKI #Workup ... #nephrology #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
esp w oliguria / GFR ... Labs: BMP (Assess GFR ... Elimination (see Table ... status to improve GFR ... sufficient if intact GFR
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
dominates → ↓ GFR ... Exclude other AKI ... Classification: HRS-AKI ... HRS-Non-AKI (formerly ... Syndrome #Hepatology #Nephrology
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