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diagnosis syndrome management oncology differential nephrology pathophysiology tumor causes potassium tumorlysis acutekidneyinjury aki uricacid acute cairoandbishop cancer classification crohns disease
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... Syndrome (TLS) ... Tumor Cell Lysis ... Hypocalcemia • Hyperkalemia ... TumorLysis #Syndrome #TLS
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Abnormalities of TLS ... Laboratory TLS ... hydroxide • Hyperkalemia
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... Massive tumor cell lysis ... TumorLysis #syndrome #TLS
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... #Presentation #TLS
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Treatment of Clinical TLS ... transfer • Tumor lysis ... MatthewHoMD #TLS ... #Tumor #Lysis #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor Lysis ... leukapheresis - TLS ... Pathophysiology: Lysis ... hydration - Hyperkalemia ... #Syndrome #TLS
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... 6L/day) • For hyperkalemia ... otherwise treat with "hyperkalemia ... wandering_er #Tumor #Lysis ... #Syndrome #TLS
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... above #Tumor #Lysis ... #Syndrome #TLS
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... transfusion • Tumor lysis ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related • Hypercalcemia ... • Light chain (LC ... nephropathy • LC ... DD • Proximal LC ... Interleukin-2) • Tumor lysis
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