28 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... (DITMA) - TMA ... • Catastrophic APLS ... #differential #diagnosis ... #hematology #hemolysis
Transposition of Great Arteries (TGA) on Chest XRay
 - Oval Shaped Cardiac Silhouette 
 - Narrow
Great Arteries (TGA ... - Oval Shaped Cardiac ... GreatArteries #TGA ... #CXR #ChestXRay ... #Radiology #Diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Anti-cardiolipin (aCl ... Anti-centromere, Scl ... Autoantibodies #Rheumatology ... #diagnosis #associations
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
thromboembolism → Cardiac ... rhythm monitoring, Echocardiogram ... CBC, aPTT, +/- CXR ... #diagnosis #algorithm ... #hematology #VTE
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - PNH - APLS ... - EGPA - MPA ... #Differential #Diagnosis ... #hematology #rheumatology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
TMA is a triad of ... and secondary TMA ... Cr>2.3 & platelets ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... have fever - ACS ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... unless severe APLS ... fluid overload, PCC ... #management #hematology
Cardiac Standstill on POCUS during CPR

A 79yo male presents after being found unresponsive by his wife.
Cardiac Standstill ... ACLS performed x ... activity p 30min ACLS ... #POCUS #CPR #Echoardiogram ... #ACLS #S4C #Intraarrest
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
LMCA lesion -> Cardiac ... revascularization (PCI ... coronary syndrome (ACS ... Angina #ChestPain #Diagnosis