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differential lupus erythematosus systemic symptoms oncology treatment classification dermatology hemophagocytic hlh leukemia lymphohistiocytosis summary vasculitis algorithm ana antinuclear arthritis autoantibodies
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Associated - SLE ... #hematology #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... #Summary #diagnosis ... #rheumatology # ... management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... thromboembolic disease ... Abnormalities: macrocytic anemia ... Autoinflammatory #Somatic #rheumatology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... diet, Alcoholism, Tea-toast ... Algorithm #ferritin #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... erythematosus [SLE ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #differential #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... , Behçet's syndrome ... Inflammation of ear ... #differential #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... Giant retinal tears ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... erythematosus (SLE ... ) Signs / Symptoms ... - Decreased tear ... Pathophysiology #Diagnosis
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