16 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... ) Blood (75%): Anemia ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... HUS • DIC • Vasculitis ... #Causes #Hematology
Reactive Skin Rash - Differential Diagnosis Algorithm
Reactive erythematous with various morphology
 • Urticaria - Firm /
Reactive Skin Rash ... Erythema Nodosum - Tender ... #Reactive #SkinRash ... #dermatology #Differential ... #causes
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
insufficiency • Vasculitis ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... Differential Diagnosis Algorithm ... • Bullous systemic ... Vesiculobullous #SkinRash ... #causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Disease Vascular System ... • Steroids • Vasculitis ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... mucositis - Rash ... purpura: strong sign ... diminished, or tender ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... - Hemolytic anemia ... autoantibodies #signs ... #differential #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... tender, red or ... Episcleritis Signs ... Causes: - Idiopathic ... Leukocytoclastic vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... diminished, or tender ... , mucositis • Rash ... tract, and often causes ... Differential #Diagnosis #Rheumatology