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Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... reticulocytes • Hemolysis ... • Blood smear: Differential ... Anemia #diagnosis #management ... #treatment #rheumatology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... #Algorithm #Differential ... Causes #Workup #Hematology ... GrepMed Recommended Text
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA #Treatment ... #management #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Diagnosis #Algorithm #hematology
Hypereosinophilia (HE) Summary • Definition • When to Suspect? • A Partial Classification of Hypereosinophilia •
• A Partial Classification ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Anemia #Differential ... Diagnosis #causes #classification ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... • Bleeding • Hemolysis ... #Anemia #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Laboratory Tests ... Urobilinogen #Hemolysis ... #Differential # ... Diagnosis #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Diagnosis and Management ... Direct antiglobulin test ... #Diagnosis #Management ... #Algorithm #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... hemorrhage and hemolysis ... indirect antiglobulin tests ... WBC count and differential ... Diagnosis #Workup #Hematology
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