16 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Demyelinating Syndrome ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 โ€ข Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... #Systemic #Erythematosus ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 โ€ข Associated
Systemic Lupus Erythematosus ... #Systemic #Lupus ... #Erythematosus ... Summary #diagnosis #rheumatology ... #management
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus ( ... #differential #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... small and large bowel ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     โ€ข
Stevens-Johnson Syndrome ... โ€ข Systemic lupus ... erythematosus ... โ€ข Inflammatory bowel ... Diagnosis #Algorithm #causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus โ†’ like
erythematosus ( ... SLE), Sjogren's Syndrome ... Arthritis, Sjรถgren Syndrome ... , Inflammatory Bowel ... ANA #patterns #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 โ€ข Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... erythematosus ( ... (SPA) โ€ข Other Causes ... Differential #Diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... SJIA], systemic lupus ... erythematosus [ ... #Diagnosis #Management ... #Hematology #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... pericarditis ยป is...lupus ... including in children (pediatric ... #system #erythematosus ... #rheumatology