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diagnosis hematology management algorithm eular2019 thrombosis anemia anticoagulation aplastic apml arterial associations autoantibodies cancer cerebritis cns differential differentiation embolism emergencies
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... 1 of the three aPLs ... diagnosed with APS ... to be present Treatment ... #Syndrome #APS
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Syndrome) APS ... #Syndrome #APS ... management #EULAR2019 #guidelines ... #rheumatology # ... hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS Previous Thrombosis? Previous Pregnancy Complications? Dr. Laurent ARNAUD @Lupusreference #obstetrics
Syndrome) APS ... #Syndrome #APS ... management #EULAR2019 #guidelines ... #rheumatology # ... obgyn #treatment
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome ... LAC) • Sjogren Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... unless severe APLS ... #oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... antibodies (APLS ... pathophysiology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Workup Algorithm INDICATIONS ... ARUPConsult @ARUPLabs #APLS ... #Antiphospholipid
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
to repair DNA, as ... - Antithyroid medications ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... after CRS) - Treatment ... AML (~20 %) and APL ... #Emergencies #Oncology
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