85 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
Raynaud Phenomenon Differential ... Diagnosis: Rheumatologic ... state (eg APLA) - Vascular ... - Frostbite #Diagnosis ... #Differential
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... sounds, RUQ pain • Dermatologic ... Clonus (inducible), Muscular ... Symptoms #spectrum #signs ... #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Renal Disease Vascular ... TeIangiectasia Vascular ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
hemolytic uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis ... #Differential #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
, holster sign, ... anti-synthetase syndrome ... - Classic triad ... at diagnosis). ... #rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm ... Signs of anemia ... #Diagnosis #Algorithm ... #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... anemia" • HELLP syndrome ... #schistocytes #differential ... #diagnosis #hematology
Causes of Vaginal Discharge - Differential Diagnosis Algorithm
Neoplastic:
 • Endometrium
 • Cervix
 • Vulva
 • Vagina
Systemic
Vaginal Discharge - Differential ... Diagnosis Algorithm ... disease • Collagen vascular ... disease • Dermatologic ... vaginalis Toxic Shock Syndrome