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diagnosis differential management vasculitis comparison algorithm lupus ana antinuclear erythematosus sle systemic treatment antibodies thrombocytopenia patterns pharmacology workup antibody autoantibodies
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... 100%, PR3+ 50%, frequently ... Hydralazine-induced ANCA ... @AnnKumfer #ANCA ... #Diagnosis #Rheumatology
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA doi:10.1038/s41572-020-0204-y #ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... s41572-020-0204-y #ANCA ... #Eosinophilic #rheumatology ... diagnosis #comparison #table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Vasculitis: P-ANCA ... perinuclear), C-ANCA ... Autoantibodies #Rheumatology ... #associations #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... Antinuclear #Antibody #ANCA ... antibodies #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... Graves' disease c-ANCA ... granulomatosis p-ANCA ... diseases #diagnosis #table ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... diagnosis #algorithm #rheumatology
Summary of haemotology cell lineages and the malignancies associated with them. Visit gramproject.com for more medical
Summary of haemotology ... medical diagrams, tables ... #algorithm #hematology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Antinuclear Antibody (ANA ... Pleuritis) H Hematologic ... erythematosus #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... StanfordChiefs #ANCA ... diagnosis #algorithm #rheumatology
Frequency of ANCA Positivity in Different Conditions ANCA-Associated Vasculitis • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
Frequency of ANCA ... • GPA - PR3-ANCA ... 75%, MPO-ANCA 20% ... , 5% ANCA negative ... PR3 #diagnosis #rheumatology
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