46 results
diagnosis signs causes management algorithm hepatology hypercalcemia neurology hematology msk primary syndrome workup alkaline alp growthhormone hyperthyroidism oncology pagetsdisease phosphatase
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... Incr IGF1 • Bone ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Cardiovascular disease ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
signs, Fragile bones ... easily/weakness, Bone ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... • GH stimulates ... Differential Diagnosis ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - Differential ... • Cushing's Disease ... • GH Deficiency ... Chemotherapy • Bone ... Diagnosis #Algorithm #endocrinology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... - Highest • Bone ... Most common symptoms ... - Bone symptoms ... ALP #Elevation #Differential
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
due to increased bone ... failure, Addison's disease ... Granulomatous diseases ... Hypercalcemia #Causes #differential ... calcium #high #endocrinology
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
, Kidney Disease ... - Accelerated Bone ... Formation: Hungy Bone ... Diagnosis #Management #endocrinology ... #differential #
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
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