38 results
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Algorithm Elevated ... Granulomatous Disease ... Miscellaneous - Bone ... #Algorithm #causes ... #endocrinology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Bone Lesion on X-Ray - Differential Diagnosis Algorithm 
Exostotic
 • Osteochondroma
Asymptomatic &/or Non-Active Bone Scam
 •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... Constitutional Symptoms ... #Causes
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... due to increased bone ... failure, Addison's disease ... #differential #diagnosis ... calcium #high #endocrinology
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Algorithm True ... • Meniere's Disease ... Media • Temporal Bone ... #Algorithm #Causes
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... - Accelerated Bone ... Formation: Hungy Bone ... #Management #endocrinology ... #differential #algorithm
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
D) Increased bone ... of bone Malignancy ... Multiple myeloma (bone ... #endocrinology ... #diagnosis #differential
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Algorithm Tumours ... - See Bone Lesions ... • Bone Marrow ... #Causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver, bone ... Most cases diagnosed ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... excessive bone ... turnover -> Incr bone ... pathophysiology #diagnosis ... #signs #symptoms