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rheumatology dermatology management differential symptoms syndrome table vasculitis manifestations classification dermatomyositis druginduced erythematosus oncology photo systemic algorithm antimda5 antimda5dm antinxp2
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... dermatomyositis, SLE ... #differential #diagnosis ... #clinical #skin
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... lesions and plaques ... hair follicles -> causes ... inflammation on skin ... #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Rare (SSA+ for cutaneous ... Discontinuation of causal ... #sle #comparison ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... papulosquamous lesions ... Differential Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... vasculitis) • Cutaneous ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic ... ’s syndrome - Lupus
Clinical Characteristics of Simple vs Complex Cutaneous Leishmaniasis Simple CL - Caused by a Leishmania species
Clinical Characteristics ... Simple vs Complex Cutaneous ... Simple CL - Caused ... Leishmaniasis #diagnosis ... #comparison #table
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... - Differential Diagnosis ... Auspitz sign, Koebner's ... soles • Discoid Lupus ... #Algorithm #causes
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